Steady Steps Toward Renewal, Momentum Into Waves | DTX 2025 Annual Review

Those who walk deeper into the cycle always spot the next beam of light.

This year, the industry's tides may not have crashed with dramatic force, but undercurrents steadily propelled those who dared to explore forward.

For Daton, 2025 was a year of putting down roots — maintaining rhythm amid volatility, and seeking new variables within certainty. It was also a year of building reserves, with long-termism as our anchor, allowing every act of persistence to accumulate momentum over time, eventually becoming a surging force driving us ahead.

This marks our tenth year, and the prologue to the next decade. Below, we look back on 2025 — a year of stories about perseverance and breakthroughs.

— Daton, ever moving forward

01 Annual Theme

Steady Progress Toward the New, Accumulated Momentum Into Waves

Daton's Perspective on Steadiness and Innovation

"Steady progress" is not conservatism, but a commitment to long-term value.

"Innovation" is not recklessness, but upward breakthrough born from deep insight.

When steadiness and innovation interact, potential energy quietly accumulates over time, eventually manifesting as "waves."

In 2025, Daton maintained patience through cycles, judgment amid complexity, and decisive action at critical moments — always rooted in the life sciences track, pressing deeper.

02 New & Increased Investments (Selected)

Deepening Hard Tech, Focusing on High Value

In 2025, centered on biomanufacturing, ophthalmology, critical and emergency care, biopharmaceuticals, embodied intelligence, and brain-computer interfaces, we continued to deepen our presence. Our investment approach followed three core logics:

  • "Engineering capability" driven by hard tech
  • "Clinical value" validated globally
  • "Systemic innovation" through platformization

Biomanufacturing Portfolio

Ophthalmology Portfolio

Critical & Emergency Care Portfolio

Biopharmaceuticals Portfolio

Embodied Intelligence Portfolio

Brain-Computer Interface Portfolio

03 Follow-on Rounds (Selected)

Accompanying Growth, Continuous Empowerment

Hanno Medical

The only domestic innovator with independent R&D and manufacturing capabilities for ECMO systems and supporting consumables

Lanji Medical

A next-generation high-end medical device company integrating optics, mechanics, electronics, and computing

Juhuan Technology

A platform for high-performance absorbable medical devices and regenerative medicine materials

Meiliweiye

A leader in radiofrequency ablation for neurology

Xuanyu Medical

An innovative medical device platform for cardiac electrophysiology and vascular intervention

Astribot

Next-generation AI humanoid robots

Rui'anxing

AI-driven surgical anesthesia robots

Jinqin Zhizao

Next-generation precision universal laparoscopic surgical instruments

Kerike Gene

Focused on innovative ophthalmic gene therapy technologies

Yuantian Biology

A leader in enzymatic waste plastic recycling

Bingjing Intelligence

A leading company in intelligent cardiac interventional imaging

Zhiting

The world's first adaptive intelligent medical-grade hearing aid

Bochuang Biology

Committed to becoming a national leader in bio-tissue functional membrane production and R&D translation

Rushen Robotics

A platform for R&D and industrialization of embodied intelligent robots restructured for elderly care scenarios

04 Portfolio Company Highlights

Stars Shining, Fruits Abundant

Globalization and International Certifications

Vitotrol Bio

Bio-vitrification cryopreservation and thawing reagents receive EU CE certification

Hanuo Medical

ECMO system receives EU MDR certification; obtains TÜV SÜD MDR certificate, accelerating globalization

He Yuan Biotechnology

Inaticabtagene autoleucel injection receives Saudi FDA Breakthrough Therapy designation

StarSea Medical

Partners with Olympus in global single-use urology products

2

Strategic Launches & Commercial Breakthroughs

Shuimu Molecule

Partners with Tsinghua AIR to globally debut biopharma intelligent agent strategy

Xuanyu Medical

China's first multi-channel / large-lesion / targeted ablation PFA system approved

Astribot

Debuts DuoCore-WB whole-body mobile manipulation model; lands one of China's first humanoid robot orders at the thousand-unit scale

Triastek

Receives China's first 3D-printed pharmaceutical production license

Yuantian Bio

First globally to achieve GRS certification for bio-based recycling technology

Bingjing Intelligent

Single-use intracardiac echocardiography catheter receives NMPA medical device registration certificate

Xiran Medical

China's first self-developed phacoemulsification-vitrectomy combined system approved for market

He Yuan Biotechnology

Inaticabtagene autoleucel injection for pediatric acute lymphoblastic leukemia receives Breakthrough Therapy designation; dual-indication CAR-T new drug approved for market, becoming China's only CAR-T cell therapy product covering both leukemia and lymphoma indications; Yuanruida® (inaticabtagene autoleucel injection) successfully included in National Healthcare Security Administration's commercial insurance innovative drug catalog

3

Government Visits & Industry Recognition

He Yuan Biotechnology

Tianjin Party Secretary Chen Min'er and Mayor Zhang Gong visit He Yuan Biotechnology for inspection and guidance

Deepwise Healthcare

Visited by Zhejiang Deputy Party Secretary and Governor Liu Jie

Landing Medical

Hubei Party Secretary Wang Zhonglin inspects Landing Medical; AI cervical cancer screening technology receives high praise

Kangyuan Medical

Participates in enterprise symposium chaired by Liaoning Party Secretary Xu Kunlin

OUR United Healthcare

TaiChiPro shortlisted for U.S. Prix Galien

Landing Medical

Selected for Forbes China AI Tech Enterprises TOP 50 2025

Jichen Biotechnology

Shortlisted for Ministry of Industry and Information Technology's "Open Competition for Leadership" program

05

Industry Recognition

Professional Endorsement, Building Momentum

Zero2IPO

  • 2025 China Top 30 Early-Stage Investment Institutions
  • 2025 China Top 30 Healthcare Investment Institutions

ChinaVenture

  • China Best Early-Stage VC Institutions TOP 10
  • China Best Medical Device Sector Investment Institutions TOP 20
  • China Best Early-Stage Investors TOP 50 (Sun Qi)
  • China Best Healthcare Industry Investors TOP 20 (Sun Qi)
  • Yangtze River Delta Best Early-Stage VC Institutions TOP 10

Rongzi China

  • China Top 100 VC Institutions
  • China Best Healthcare Sector Investment Institutions
  • China Best Investors TOP 100 (Sun Qi)

Global Entrepreneurship Week China Organizing Committee

  • Annual Top 30 Angel Investors (Sun Qi)

China Securities Journal

  • Biomedical Sector Investment Institution Golden Bull Award

Yicai

  • Outstanding Life Sciences & Healthcare Investment Institutions TOP 10
  • Best Investment Institutions TOP 50

Global PE Forum

  • Annual Top 20 Most Active China Healthcare Investment Institutions

Touzijia

  • Annual Best Early-Stage Investment Institutions TOP 40
  • Annual Best Early-Stage Investors TOP 25 (Huang Ning)

VBData

  • Annual Healthcare Leadership Investment Institutions
  • Annual Healthcare Leadership Investors (Sun Qi)

Shanghai International Private Equity Investment Fund Association

  • Shanghai Best Annual VC Investment Institutions
  • Shanghai Best Annual Life Sciences & Healthcare Investment Institutions
  • Shanghai Best Annual Investor — Sun Qi

Healthcare Investment Excellence Awards

  • Annual Best Innovative Medical Device Investment Institutions
  • Annual Best Biotechnology Investment Institutions
  • Annual Healthcare Investors (Sun Qi)

TMTpost

  • H1 Early-Stage Investment Pioneer Institutions TOP 20
  • H1 Early-Stage Fundraising Pioneer Institutions TOP 10
  • 2025 H1 Healthcare Sector Pioneers TOP 20

Qimingpian

  • Annual China Best Early-Stage Investment Institutions — Comprehensive Ranking TOP 30
  • Annual China Best Early-Stage Investment Institutions — Activity Ranking TOP 30
  • Annual China Best Healthcare Sector Investment Institutions TOP 10
  • Annual China Best Investors TOP 100 (Sun Qi)

Diyixinsheng

  • Annual China Most Active Early-Stage Investment Institutions TOP 30
  • Annual Healthcare Most Active Investment Institutions TOP 20
  • Annual China Best Sector Investors (Sun Qi)

06

Brand Column

Jointly Created, Amplifying Voices

In 2025, we partnered with tech media platform Pencil News to launch the "Unicorns of the New Era" joint column, systematically identifying and promoting outstanding companies with breakthrough technologies, innovative business models, and high growth potential. Click the links below to read the original reports:

Xinyun Medical | Beijing Future Unicorn Taps 500 Billion RMB Pain Treatment Market, Secures New Funding Round

Yuantian Biotech | Yet Another Funding Round! Fujian Post-88 PhD Cracks Plastic Waste Recycling: Three Rounds in One Year, a National First

Rushen Robotics | Academic's Student Builds Wellness Robots: Enters 10 Billion RMB Market, Secures Tens of Millions in First Round

Weiyuan Biotech | Zhejiang University Alumnus Builds "Bio-Chip," Enters 100 Billion Dollar Mega-Market, Nears 100 Million in First Round

Unicorns of the New Era

07

Brand Milestones

Events & Ecosystem

In 2025, Daotong marks its tenth anniversary! We connected industry, capital, and innovation through a series of events:

2025 CEO Summit (Hong Kong)

Supported by the Hong Kong Innovation, Technology and Industry Bureau, InvestHK, and other institutions, helping portfolio companies deepen their presence in the Hong Kong market.

Tenth Anniversary Forum (Shanghai)

Bringing together academicians, industry leaders, top scientists, and entrepreneurs to reflect on ten years of sector conviction and discuss future opportunities.

Bio-Manufacturing CVC Fund Launch

Partnered with OPM Biosciences to launch Shanghai's first bio-manufacturing industry fund, supporting the development of a high-end bio-manufacturing cluster.

Bio-Manufacturing Industry Value Partners Alliance Established

Founding members include seven organizations from industry, academia, research, and investment, aimed at driving the "technology — scenario — capital" cycle into practice.

08

Year-End Letter, 2025

A Decade's Prologue, Setting Out Anew

Those who walk deep into the cycle always catch the next glimmer of light.

Ten years ago, we started from a blank sheet — nothing but a wish and reverence for the industry.

Ten years on, we look back at this road —

It was never smooth, yet everywhere it flickers with light, validated by time.

The hard calls, the directions we held to, the founders we stood beside, the ups and downs —

all now settled into Dalton Venture's foundation:

Innovation. Resilience. Pragmatism. Focus.

2025 is our tenth year,

and the prologue to the next.

Before the coming wave,

we choose to keep moving — steady, yet ever-renewing;

in the long river of time,

quietly building momentum, until it swells.

Ten years together — thank you for walking with us.

The new decade: let's surge further, together.

Steady Steps, Renewed Vision; Momentum Built, Tides Made

DALTON VENTURE

WeChat Official Account | Dalton Venture

Account ID | daltonventure

END