Company

Kaiwuji

开物纪

Kaiwuji (开物纪) is an AI-for-Science startup using scaled AI models to discover, mass-produce, and commercialize new materials — in founder Lu Ziheng's own words, "materials that could change humanity's fate." Lu, a materials scientist who left Microsoft Research in 2025 where he worked on AI4S, founded the company (registered September 2025); he also serves as chief materials scientist at the Beijing Zhongguancun Academy. His co-founder Yang Mengyang also came from Microsoft, having worked at its UK office. As of the April 2026 interview with 十字路口Crossing, the team was about ten people with zero revenue — yet its angel+ round, in which BlueRun Ventures led the angel and doubled down, reached hundreds of millions of RMB. Lu frames the raise as a bet on timing: model capabilities have improved enough that genuinely civilization-shifting materials may be within reach. The space is crowded — overseas Periodic Labs, Bezos-backed Project Prometheus, CuspAI and Orbital Materials; at home, DeepWise and 深度原理.

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KaiwujiCompany
开物纪
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