Chenru Duan
段辰儒
Chenru Duan is co-founder and CTO of Deep Principle Technology (深度原理), an AI-driven chemistry and materials science startup. He holds a PhD in physical chemistry from MIT and previously worked as a research scientist at Microsoft, where he deployed computational chemistry and AI solutions for chemical materials companies . Alongside co-founder and CEO Haojun Jia, Duan leads a team drawn from MIT, Stanford, Zhejiang University, Fudan, and companies including Microsoft, Meta, Dow Chemical, and BASF . Linear Capital led Deep Principle's nearly $10 million seed round in 2024, and Hillhouse exclusively invested in its seed+ round later that year . In June 2025, Duan and Jia attended the Davos Summer Forum as the only AI4S (AI for Science) company invited worldwide, including a panel discussion with Premier Li Qiang .
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Coverage
"Deep Principle" Closes Series A2 Round, Joins OpenAI and Others in *Science* to Discuss AI4S Exploration | Linear Portfolio
AI4S shouldn't stop at the "selling shovels" stage.
线性资本·In Sync with OpenAI, "Deep Principle" Leads 24 Top Global Institutions in Releasing LLMs for Science Benchmark | Linear Portfolio
Can high scores on test banks actually power scientific discovery?
线性资本·Where Are the Opportunities for China's AI4S Industry in Trump's "Genesis Project"? | Linear Voice
Standing at the historical inflection point of a new Age of Scientific Discovery.
线性资本·Linear Capital's 2025 Investor Conference Successfully Held in Beijing | Linear News
To be or not to be, in the AI-dominated future.
线性资本·The Only AI4S Company Invited Worldwide, "Deep Principle" Attends Davos Summer Forum Panel Discussion | Linear Portfolio
and was selected as a Technology Pioneer by the World Economic Forum at Davos in 2025.
线性资本·Linear Capital seed-stage portfolio company Deep Principle, an AI-driven chemistry and materials science enterprise, has completed a seed+ round with an exclusive investment from Hillhouse.
AI Reshapes the R&D Process for Novel Chemical Materials
线性资本·Transforming the Industrial Landscape of Chemical Materials with AI | Linear Capital Portfolio Interview Series: "Deep Principle Technology"
Today, Deep Principle, a company focused on AI-driven scientific research in chemistry, announced the completion of a nearly $10 million seed funding round. Linear Capital led the round, with Zhenzhi Ventures and Taihill Venture participating as co-investors. XtalPi and DP Technology also joined as strategic industry investors. Founded in 2024, Deep Principle's founding members are all graduates of MIT. The company's vision is to integrate artificial intelligence, quantum...
线性资本·Using AI to Accelerate Discovery of Efficient Catalytic Materials, "Deep Principle Technology" Raises Nearly $10 Million in Seed Funding Led by Linear Capital
By Chen Sida | Edited by Deng Yongyi Source: Intelligent Emergence From household daily chemical products to high-efficiency catalysis for energy use, nearly every aspect of life and production depends on emerging materials. The old "needle in a haystack" trial-and-error approach can no longer meet today's materials R&D demands. But the AI boom sparked by the large model wave is bringing "AI alchemy" closer to reality.
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